Publications

Mol Cell
2022
The human mitochondrial genome contains a second light strand promoter

NAR
2022
Ribonucleotides embedded in template DNA impair mitochondrial RNA polymerase progression

Nature Comm
2021
POLRMT mutations impair mitochondrial transcription causing neurological disease

Nature
2020
Small-molecule inhibitors of human mitochondrial DNA transcription

Mol Cell
2018
Topoisomerase 3α Is required for decatenation and segregation of human mtDNA

SLAS Discovery
2017
An adaptable high-throughput technology enabling the identification of specific transcription modulators