Selected publications:
Mol Cell
2022
The human mitochondrial genome contains a second light strand promoter
NAR
2022
Ribonucleotides embedded in template DNA impair mitochondrial RNA polymerase progression
Nature Comm
2021
POLRMT mutations impair mitochondrial transcription causing neurological disease
Nature
2020
Small-molecule inhibitors of human mitochondrial DNA transcription
Mol Cell
2018
Topoisomerase 3α Is required for decatenation and segregation of human mtDNA
SLAS Discovery
2017
An adaptable high-throughput technology enabling the identification of specific transcription modulators