Selected publications:
Nature
2025
Small molecules restore mutant mitochondrial DNA polymerase activity
Annu Rev Biochem
2024
Replication and transcription of human mitochondrial DNA
Mol Cell
2022
The human mitochondrial genome contains a second light strand promoter
Nature Comm
2021
POLRMT mutations impair mitochondrial transcription causing neurological disease
Nature
2020
Small-molecule inhibitors of human mitochondrial DNA transcription
Mol Cell
2018
Topoisomerase 3α Is required for decatenation and segregation of human mtDNA