FEATURED ARTICLES
POLRMT mutations impair mitochondrial transcription causing neurological disease.
Nat Comm 2021 Feb 18;12(1):1135. doi: 10.1038/s41467-021-21279-0
Small-molecule inhibitors of human mitochondrial DNA transcription.
Nature 2020 Dec;588(7839):712-716. doi: 10.1038/s41586-020-03048-z
RNase H1 directs origin-specific initiation of DNA replication in human mitochondria.
PLoS Genetics 2019 Jan 3; https://doi.org/10.1371/journal.pgen.1007781
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Mol Cell 2017 Dec 28; doi.org/10.1016/j.molcel.2017.11.033
POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.
Sci Adv 2016 Aug 5;2(8):e1600963. doi: 10.1126/sciadv.1600963
Maintenance and expression of mammalian mitochondrial DNA.
Annual Review of Biochemistry 2016 Vol.85:133-160
GUSTAFSSON lab 